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Phenotyping drug polypharmacology via eicosanoid profiling of blood
It is widely accepted that small-molecule drugs, despite their selectivity at primary targets, exert pharmacological effects (and safety liabilities) through a multiplicity of pathways. As such, it has proved extremely difficult to experimentally assess polypharmacology in an agnostic fashion. Profi...
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| Publicado no: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513990/ https://ncbi.nlm.nih.gov/pubmed/26022804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058677 |
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