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RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression

From the first reported role of the transcription factor RUNX2 in osteoblast and chondrocyte differentiation and migration to its involvement in promigratory/proinvasive behavior of breast, prostate, and thyroid cancer cells, osteosarcoma, or melanoma cells, RUNX2 currently emerges as a key player i...

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Publicado en:Mol Cancer
Autores principales: Cohen-Solal, Karine A., Boregowda, Rajeev K., Lasfar, Ahmed
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513933/
https://ncbi.nlm.nih.gov/pubmed/26204939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0404-3
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