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Post-translational environmental switch of RadA activity by extein–intein interactions in protein splicing

Post-translational control based on an environmentally sensitive intervening intein sequence is described. Inteins are invasive genetic elements that self-splice at the protein level from the flanking host protein, the exteins. Here we show in Escherichia coli and in vitro that splicing of the RadA...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Topilina, Natalya I., Novikova, Olga, Stanger, Matthew, Banavali, Nilesh K., Belfort, Marlene
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513877/
https://ncbi.nlm.nih.gov/pubmed/26101259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv612
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