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The polyclonal CD8 T cell response to influenza M1(58–66) generates a fully connected network of cross-reactive clonotypes to structurally related peptides: A paradigm for memory repertoire coverage of novel epitopes or escape mutants()

Cross-reactivity of T cells is defined by recognition of two or more peptide-MHC complexes by the same T cell. Although examples of cross-reactivity have been reported, a detailed examination of cross-reactivity has not been performed. Here we take advantage of the high degree of polyclonality in th...

詳細記述

保存先:
書誌詳細
出版年:J Immunol
主要な著者: Petrova, Galina V., Naumova, Elena N., Gorski, Jack
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513670/
https://ncbi.nlm.nih.gov/pubmed/21518969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004031
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