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Chaperoning of the A(1)-Adenosine Receptor by Endogenous Adenosine—An Extension of the Retaliatory Metabolite Concept()
Cell-permeable orthosteric ligands can assist folding of G protein–coupled receptors in the endoplasmic reticulum (ER); this pharmacochaperoning translates into increased cell surface levels of receptors. Here we used a folding-defective mutant of human A(1)-adenosine receptor as a sensor to explore...
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| 出版年: | Mol Pharmacol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513639/ https://ncbi.nlm.nih.gov/pubmed/25354767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.094045 |
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