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RE-IIBP Methylates H3K79 and Induces MEIS1-mediated Apoptosis via H2BK120 Ubiquitination by RNF20

Histone lysine methylation contributes to transcriptional regulation by serving as a platform for the recruitment of various cofactors. Intense studies have been conducted for elucidating the functional meaning of H3K79 methylation, and to date, the only known HMTase responsible for the modification...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Woo Park, Jin, Kim, Kee-Beom, Kim, Ji-Young, Chae, Yun-Cheol, Jeong, Oh-Seok, Seo, Sang-Beom
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513340/
https://ncbi.nlm.nih.gov/pubmed/26206755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12485
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