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Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis
The actin cytoskeleton is important for platelet biogenesis. Tropomodulin-3 (Tmod3), the only Tmod isoform detected in platelets and megakaryocytes (MKs), caps actin filament (F-actin) pointed ends and binds tropomyosins (TMs), regulating actin polymerization and stability. To determine the function...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513252/ https://ncbi.nlm.nih.gov/pubmed/25964668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-601484 |
| タグ: |
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