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Vibrio vulnificus Secretes an Insulin-degrading Enzyme That Promotes Bacterial Proliferation in Vivo

We describe a novel insulin-degrading enzyme, SidC, that contributes to the proliferation of the human bacterial pathogen Vibrio vulnificus in a mouse model. SidC is phylogenetically distinct from other known insulin-degrading enzymes and is expressed and secreted specifically during host infection....

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Publicado en:J Biol Chem
Autores principales: Kim, In Hwang, Kim, Ik-Jung, Wen, Yancheng, Park, Na-Young, Park, Jinyoung, Lee, Keun-Woo, Koh, Ara, Lee, Ji-Hyun, Koo, Seung-Hoi, Kim, Kun-Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513127/
https://ncbi.nlm.nih.gov/pubmed/26041774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.656306
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