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Multi-Factor Regulation of the Master Modulator LeuO for the Cyclic-(Phe-Pro) Signaling Pathway in Vibrio vulnificus

LeuO plays the role of a master regulator in the cyclic-L-phenylalanine-L-proline (cFP)-dependent signaling pathway in Vibrio vulnificus. cFP, as shown through isothermal titration calorimetry analysis, binds specifically to the periplasmic domain of ToxR. Binding of cFP triggers a change in the cyt...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Park, Na-Young, Kim, In Hwang, Wen, Yancheng, Lee, Keun-Woo, Lee, Sora, Kim, Jeong-A, Jung, Kwang-Hwan, Lee, Kyu-Ho, Kim, Kun-Soo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934829/
https://ncbi.nlm.nih.gov/pubmed/31882984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56855-4
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