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Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution

Three out of ∼30 nucleoporins, Nup62, Nup54, and Nup58, line the nuclear pore channel. These “channel” nucleoporins each contain an ordered region of ∼150–200 residues, which is predicted to be segmented into 3–4 α-helical regions of ∼40–80 residues. Notably, these segmentations are evolutionarily c...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Sharma, Alok, Solmaz, Sozanne R., Blobel, Günter, Melčák, Ivo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513098/
https://ncbi.nlm.nih.gov/pubmed/26025361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.663500
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