Genetic and pharmacologic inhibition of Tpl2 kinase is protective in a mouse model of ventilator-induced lung injury

BACKGROUND: Mechanical stress induced by injurious ventilation leads to pro-inflammatory cytokine production and lung injury. The extracellular-signal-regulated-kinase, ERK1/2, participates in the signaling pathways activated upon mechanical stress in the lungs to promote the inflammatory response....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Intensive Care Med Exp
Main Authors: Kaniaris, Evangelos, Vaporidi, Katerina, Vergadi, Eleni, Theodorakis, Emmanuel E, Kondili, Eumorfia, Lagoudaki, Eleni, Tsatsanis, Christos, Georgopoulos, Dimitris
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513004/
https://ncbi.nlm.nih.gov/pubmed/26266915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-2-15
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker