Plasma Cytokine and Angiogenic Factor Profiling Identifies Markers Associated with Tumor Shrinkage in Early-Stage Non-Small Cell Lung Cancer Patients Treated with Pazopanib

There is an unmet need for pharmacodynamic and predictive biomarkers for antiangiogenic agents. Recent studies have shown that soluble vascular endothelial growth factor receptor 2 (sVEGFR2), VEGF, and several other soluble factors may be modulated by VEGF pathway inhibitors. We conducted a broad pr...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Nikolinakos, Petros G., Altorki, Nasser, Yankelevitz, David, Tran, Hai T., Yan, Shaoyu, Rajagopalan, Dilip, Bordogna, Walter, Ottesen, Lone H., Heymach, John V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512950/
https://ncbi.nlm.nih.gov/pubmed/20215520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2533
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