Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy

BACKGROUND: Pazopanib achieved the end point of clinical activity in pretreated patients with urothelial cancer in a single-group, phase 2 trial. The objective was to identify biological predictors of clinical benefit to pazopanib in these patients. METHODS: EDTA blood samples were collected at base...

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Detalhes bibliográficos
Main Authors: Necchi, A, Pennati, M, Zaffaroni, N, Landoni, E, Giannatempo, P, Raggi, D, Schwartz, L H, Morosi, C, Crippa, F, Farè, E, Nicolai, N, Lanocita, R, Sava, T, Sacco, C, Messina, C, Ortega, C, De Braud, F G, Salvioni, R, Daidone, M G, Gianni, A M, Mariani, L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887307/
https://ncbi.nlm.nih.gov/pubmed/24231947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.719
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