Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the metabolism of SSRIs, thereby affecting drug efficacy and safety. We summarize evidence from the published literature supporting...

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發表在:Clin Pharmacol Ther
Main Authors: Hicks, JK, Bishop, JR, Sangkuhl, K, Müller, DJ, Ji, Y, Leckband, SG, Leeder, JS, Graham, RL, Chiulli, DL, LLerena, A, Skaar, TC, Scott, SA, Stingl, JC, Klein, TE, Caudle, KE, Gaedigk, A
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
主題:
CPIC Guidelines
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512908/
https://ncbi.nlm.nih.gov/pubmed/25974703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.147
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