Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

Selective serotonin reuptake inhibitors (SSRIs) are primary treatment options for major depressive and anxiety disorders. CYP2D6 and CYP2C19 polymorphisms can influence the metabolism of SSRIs, thereby affecting drug efficacy and safety. We summarize evidence from the published literature supporting...

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Bibliografski detalji
Izdano u:Clin Pharmacol Ther
Glavni autori: Hicks, JK, Bishop, JR, Sangkuhl, K, Müller, DJ, Ji, Y, Leckband, SG, Leeder, JS, Graham, RL, Chiulli, DL, LLerena, A, Skaar, TC, Scott, SA, Stingl, JC, Klein, TE, Caudle, KE, Gaedigk, A
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
CPIC Guidelines
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512908/
https://ncbi.nlm.nih.gov/pubmed/25974703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.147
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