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Modeling the spatiotemporal dynamics of light and heat propagation for in vivo optogenetics

Despite the increasing use of optogenetics in vivo, the effects of direct light exposure to brain tissue are understudied. Of particular concern is the potential for heat induced by prolonged optical stimulation. We demonstrate that high intensity light, delivered through an optical fiber, is capabl...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Stujenske, Joseph M., Spellman, Timothy, Gordon, Joshua A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512881/
https://ncbi.nlm.nih.gov/pubmed/26166563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.036
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