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Spatiotemporal dynamics of optogenetically induced and spontaneous seizure transitions in primary generalized epilepsy

Transitions into primary generalized epileptic seizures occur abruptly and synchronously across the brain. Their potential triggers remain unknown. We used optogenetics to causally test the hypothesis that rhythmic population bursting of excitatory neurons in a local neocortical region can rapidly t...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Wagner, Fabien B., Truccolo, Wilson, Wang, Jing, Nurmikko, Arto V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416582/
https://ncbi.nlm.nih.gov/pubmed/25552645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01040.2014
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