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S100B Up-Regulates Macrophage Production of IL1β and CCL22 and Influences Severity of Retinal Inflammation

S100B is a Ca(2+) binding protein and is typically associated with brain and CNS disorders. However, the role of S100B in an inflammatory situation is not clear. The aim of the study was to determine whether S100B is likely to influence inflammation through its effect on macrophages. A murine macrop...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Niven, Jennifer, Hoare, Joseph, McGowan, Debbie, Devarajan, Gayathri, Itohara, Shigeyoshi, Gannagé, Monique, Teismann, Peter, Crane, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512682/
https://ncbi.nlm.nih.gov/pubmed/26204512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132688
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