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IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1

S100A8/9 and S100A12 are emerging biomarkers for disease activity of autoimmune and cardiovascular diseases. We demonstrated previously that S100A12 accelerates atherosclerosis accompanied by large cholesterol deposits in atherosclerotic lesions of apoE-null mice. The objective of this study was to...

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Detalhes bibliográficos
Main Authors: Chellan, Bijoy, Yan, Ling, Sontag, Timothy J., Reardon, Catherine A., Hofmann Bowman, Marion A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934729/
https://ncbi.nlm.nih.gov/pubmed/24367046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M044305
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