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CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death
Defects in mitochondrial fission and cyclin dependent kinase 5 (CDK5) activation are early events that precede neuronal loss following NMDA-induced neuronal death. Here, we report that the cytoplasmic CDK5 tightly regulates mitochondrial morphology defects associated with NMDA-induced neuronal injur...
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| Vydáno v: | Hum Mol Genet |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512627/ https://ncbi.nlm.nih.gov/pubmed/26002103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv188 |
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