Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry

Obesity is highly heritable. Genetic variants showing robust associations with obesity traits have been identified through genome-wide association studies. We investigated whether a composite score representing healthy diet modifies associations of these variants with obesity traits. Totally, 32 bod...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Nettleton, Jennifer A., Follis, Jack L., Ngwa, Julius S., Smith, Caren E., Ahmad, Shafqat, Tanaka, Toshiko, Wojczynski, Mary K., Voortman, Trudy, Lemaitre, Rozenn N., Kristiansson, Kati, Nuotio, Marja-Liisa, Houston, Denise K., Perälä, Mia-Maria, Qi, Qibin, Sonestedt, Emily, Manichaikul, Ani, Kanoni, Stavroula, Ganna, Andrea, Mikkilä, Vera, North, Kari E., Siscovick, David S., Harald, Kennet, Mckeown, Nicola M., Johansson, Ingegerd, Rissanen, Harri, Liu, Yongmei, Lahti, Jari, Hu, Frank B., Bandinelli, Stefania, Rukh, Gull, Rich, Stephen, Booij, Lisanne, Dmitriou, Maria, Ax, Erika, Raitakari, Olli, Mukamal, Kenneth, Männistö, Satu, Hallmans, Göran, Jula, Antti, Ericson, Ulrika, Jacobs,, David R., Van Rooij, Frank J. A., Deloukas, Panos, Sjögren, Per, Kähönen, Mika, Djousse, Luc, Perola, Markus, Barroso, Inês, Hofman, Albert, Stirrups, Kathleen, Viikari, Jorma, Uitterlinden, André G., Kalafati, Ioanna P., Franco, Oscar H., Mozaffarian, Dariush, Salomaa, Veikko, Borecki, Ingrid B., Knekt, Paul, Kritchevsky, Stephen B., Eriksson, Johan G., Dedoussis, George V., Qi, Lu, Ferrucci, Luigi, Orho-Melander, Marju, Zillikens, M. Carola, Ingelsson, Erik, Lehtimäki, Terho, Renström, Frida, Cupples, L. Adrienne, Loos, Ruth J. F., Franks, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512626/
https://ncbi.nlm.nih.gov/pubmed/25994509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv186
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