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Structural analysis of leader peptide binding enables leader-free cyanobactin processing
Regioselective modification of amino acids within the context of a peptide is common to a number of biosynthetic pathways and many such products have potential as therapeutics. The ATP dependent enzyme LynD heterocyclizes multiple cysteine residues to thiazolines within a peptide substrate. The enzy...
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| Yayımlandı: | Nat Chem Biol |
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| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512242/ https://ncbi.nlm.nih.gov/pubmed/26098679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1841 |
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