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Cadherin-mediated cell interactions are necessary for the activation of MyoD in Xenopus mesoderm.

Muscle progenitors in Xenopus interact in a community of 100 or more cells to activate their myogenic genes and the muscle differentiation pathway. We examine whether the cell adhesion molecule cadherin is involved in this process. Injections of dominant negative N-cadherin RNA into the region of 2-...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Holt, C E, Lemaire, P, Gurdon, J B
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45122/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7971972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.23.10844
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