Molecular Docking studies of FKBP12-mTOR inhibitors using binding predictions

Mammalian target of rapamycin (mTOR) is a key regulator of cell growth, proliferation and angiogenesis. mTOR signaling is frequently hyper activated in a broad spectrum of human cancers thereby making it a potential drug target. The current drugs available have been successful in inhibiting the mTOR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioinformation
Hauptverfasser: Nasr, Arash Boroumand, Ponnala, Deepika, Sagurthi, Someshwar Rao, Kattamuri, Ramesh Kumar, Marri, Vijaya Kumar, Gudala, Suresh, Lakkaraju, Chandana, Bandaru, Srinivas, Nayarisseri, Anuraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biomedical Informatics 2015
Schlagworte:
Hypothesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512006/
https://ncbi.nlm.nih.gov/pubmed/26229292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011307
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