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Functional divergence of dafachronic acid pathways in the control of C. elegans development and lifespan

Steroid hormone and insulin/insulin-like growth factor signaling (IIS) pathways control development and lifespan in the nematode Caenorhabditis elegans by regulating the activity of the nuclear receptor DAF-12 and the FoxO transcription factor DAF-16, respectively. The DAF-12 ligands Δ(4)- and Δ(7)-...

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Bibliografske podrobnosti
izdano v:Dev Biol
Main Authors: Dumas, Kathleen J., Guo, Chunfang, Wang, Xi, Burkhart, Kirk B., Adams, Elizabeth J., Alam, Hena, Hu, Patrick J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511482/
https://ncbi.nlm.nih.gov/pubmed/20178781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.02.022
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