Crucial role of nicotinic α5 subunit variants for Ca(2+) fluxes in ventral midbrain neurons

Neuronal nicotinic acetylcholine receptors (nAChRs) containing the α5 subunit modulate nicotine consumption, and the human CHRNA5 rs16969968 polymorphism, causing the replacement of the aspartic acid residue at position 398 with an asparagine (α5DN), has recently been associated with increased use o...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Sciaccaluga, Miriam, Moriconi, Claudia, Martinello, Katiuscia, Catalano, Myriam, Bermudez, Isabel, Stitzel, Jerry A., Maskos, Uwe, Fucile, Sergio
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511205/
https://ncbi.nlm.nih.gov/pubmed/25911614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268102
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