A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Oral Type I Collagen Treatment in Patients With Diffuse Cutaneous Systemic Sclerosis: I. Oral Type I Collagen Does Not Improve Skin in All Patients, but May Improve Skin in Late-Phase Disease

OBJECTIVE: To investigate the safety and efficacy of oral bovine type I collagen (CI) treatment in patients who have had diffuse cutaneous systemic sclerosis (dc-SSc; scleroderma) for ≤10 years. METHODS: One hundred sixty-eight patients with dcSSc were enrolled in a double-blind, placebo-controlled...

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Detalhes bibliográficos
Publicado no:Arthritis Rheum
Main Authors: Postlethwaite, Arnold E., Wong, Weng Kee, Clements, Philip, Chatterjee, Soumya, Fessler, Barri J., Kang, Andrew H., Korn, Joseph, Mayes, Maureen, Merkel, Peter A., Molitor, Jerry A., Moreland, Larry, Rothfield, Naomi, Simms, Robert W., Smith, Edwin A., Spiera, Robert, Steen, Virginia, Warrington, Kenneth, White, Barbara, Wigley, Frederick, Furst, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511098/
https://ncbi.nlm.nih.gov/pubmed/18512816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23501
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