Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats

The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic modulators of the classical, lectin and alternative pathways of the complement system are currently in pre-clinical and clinical development....

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Sharp, Julia A., Hair, Pamela S., Pallera, Haree K., Kumar, Parvathi S., Mauriello, Clifford T., Nyalwidhe, Julius O., Phelps, Cody A., Park, Dalnam, Thielens, Nicole M., Pascal, Stephen M., Chen, Waldon, Duffy, Diane M., Lattanzio, Frank A., Cunnion, Kenji M., Krishna, Neel K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511006/
https://ncbi.nlm.nih.gov/pubmed/26196285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132446
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