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Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis

Merkel cells are mechanosensitive skin cells whose production requires the basic helix-loop-helix transcription factor Atoh1. We induced ectopic Atoh1 expression in the skin of transgenic mice to determine whether Atoh1 was sufficient to create additional Merkel cells. In embryos, ectopic Atoh1 expr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Ostrowski, Stephen M., Wright, Margaret C., Bolock, Alexa M., Geng, Xuehui, Maricich, Stephen M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510865/
https://ncbi.nlm.nih.gov/pubmed/26138479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.123141
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