The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse

IFT20, a component of the intraflagellar transport (IFT) system that controls ciliogenesis, regulates immune synapse assembly in the non-ciliated T-cell by promoting T-cell receptor (TCR) recycling. Here, we have addressed the role of Rab8 (for which there are two isoforms Rab8a and Rab8b), a small...

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Publicado en:J Cell Sci
Autores principales: Finetti, Francesca, Patrussi, Laura, Galgano, Donatella, Cassioli, Chiara, Perinetti, Giuseppe, Pazour, Gregory J., Baldari, Cosima T.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510855/
https://ncbi.nlm.nih.gov/pubmed/26034069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.171652
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