Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse

Most eukaryotic cells have a primary cilium which acts as a sensory organelle1. Cilia are assembled by intraflagellar transport (IFT), a process mediated by multimeric IFT particles and molecular motors2. Here we show that lymphoid and myeloid cells, which lack primary cilia, express IFT proteins. I...

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Bibliografiske detaljer
Main Authors: Finetti, Francesca, Paccani, Silvia Rossi, Riparbelli, Maria Giovanna, Giacomello, Emiliana, Perinetti, Giuseppe, Pazour, Gregory J., Rosenbaum, Joel, Baldari, Cosima T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837911/
https://ncbi.nlm.nih.gov/pubmed/19855387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1977
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