Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure

The cytoskeleton is widely considered essential for neurulation, yet the mouse spinal neural tube can close despite genetic and non-genetic disruption of the cytoskeleton. To investigate this apparent contradiction, we applied cytoskeletal inhibitors to mouse embryos in culture. Preventing actomyosi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Sci
Egile Nagusiak: Escuin, Sarah, Vernay, Bertrand, Savery, Dawn, Gurniak, Christine B., Witke, Walter, Greene, Nicholas D. E., Copp, Andrew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Company of Biologists 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510849/
https://ncbi.nlm.nih.gov/pubmed/26040287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.164574
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