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Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samples

Medulloblastoma is the most common pediatric brain tumor and its development is affected by genetic and epigenetic factors. In this study we found there is low or no expression of the hedgehog interacting protein (HHIP), a negative regulator of the sonic hedgehog pathway, in most medulloblastoma cel...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Shahi, Mehdi H., Afzal, Mohammad, Sinha, Subrata, Eberhart, Charles G., Rey, Juan A., Fan, Xing, Castresana, Javier S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510471/
https://ncbi.nlm.nih.gov/pubmed/20853133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0401-8
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