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Systemic and Intravitreal Delivery of Dendrimers to Activated Microglia/Macrophage in Ischemia/Reperfusion Mouse Retina

PURPOSE: Microglial activation and associated neuroinflammation play a key role in the pathogenesis of many diseases of the retina, including viral infection, diabetes, and retinal degeneration. Strategies to target activated microglia and macrophages and attenuate inflammation may be valuable in tr...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kambhampati, Siva P., Clunies-Ross, Alexander J. M., Bhutto, Imran, Mishra, Manoj K., Edwards, Malia, McLeod, D. Scott, Kannan, Rangaramanujam M., Lutty, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510469/
https://ncbi.nlm.nih.gov/pubmed/26193917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-16250
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