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Sustained Complete Response to Cytotoxic Therapy and the PARP Inhibitor Veliparib in Metastatic Castration-Resistant Prostate Cancer – A Case Report

Solid tumors harboring BRCA1 or BRCA2 mutations have been shown to respond to PARP inhibitors. These responses are partial and transient. In this case report, we describe an 82-year-old male with poorly differentiated prostate cancer with metastases to the lung, liver, abdomen, and bowel. Molecular...

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Udgivet i:Front Oncol
Main Authors: VanderWeele, David J., Paner, Gladell P., Fleming, Gini F., Szmulewitz, Russell Z.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510409/
https://ncbi.nlm.nih.gov/pubmed/26258074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00169
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