Misato Controls Mitotic Microtubule Generation by Stabilizing the Tubulin Chaperone Protein-1 Complex

Mitotic spindles are primarily composed of microtubules (MTs), generated by polymerization of α- and β-Tubulin hetero-dimers [1, 2]. Tubulins undergo a series of protein folding and post-translational modifications in order to fulfill their functions [3, 4]. Defects in Tubulin polymerization dramati...

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Udgivet i:Curr Biol
Main Authors: Palumbo, Valeria, Pellacani, Claudia, Heesom, Kate J., Rogala, Kacper B., Deane, Charlotte M., Mottier-Pavie, Violaine, Gatti, Maurizio, Bonaccorsi, Silvia, Wakefield, James G.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2015
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510148/
https://ncbi.nlm.nih.gov/pubmed/26096973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2015.05.033
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