Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites

Long interspersed elements (LINEs), through both self-mobilization and trans-mobilization of short interspersed elements and processed pseudogenes, have made an indelible impact on the structure and function of the human genome. One consequence is the creation of new CpG islands (CGIs). In fact, mor...

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Publicado en:Genome Res
Autores principales: Grandi, Fiorella C., Rosser, James M., Newkirk, Simon J., Yin, Jun, Jiang, Xiaoling, Xing, Zhuo, Whitmore, Leanne, Bashir, Sanum, Ivics, Zoltán, Izsvák, Zsuzsanna, Ye, Ping, Yu, Y. Eugene, An, Wenfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509998/
https://ncbi.nlm.nih.gov/pubmed/25995269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.185132.114
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