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MS2 coat proteins bound to yeast mRNAs block 5′ to 3′ degradation and trap mRNA decay products: implications for the localization of mRNAs by MS2-MCP system

Arrays of MS2 binding sites are placed into mRNAs and are commonly used to visualize the localization of mRNAs in vivo by the expression of an MS2-GFP fusion protein. In Saccharomyces cerevisiae, we observed that arrays of MS2 binding sites inhibit 5′ to 3′ degradation of the mRNA in yeast cells and...

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Bibliografiset tiedot
Julkaisussa:RNA
Päätekijät: Garcia, Jennifer F., Parker, Roy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509929/
https://ncbi.nlm.nih.gov/pubmed/26092944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.051797.115
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