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IGF1 Promotes Adipogenesis by a Lineage Bias of Endogenous Adipose Stem/Progenitor Cells

Adipogenesis is essential for soft tissue reconstruction following trauma or tumor resection. We demonstrate that CD31-/34+/146− cells, a subpopulation of the stromal vascular fraction (SVF) of human adipose tissue, were robustly adipogenic. Insulin Growth Factor-1 (IGF1) promoted a lineage bias tow...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Hu, Li, Yang, Guodong, Hägg, Daniel, Sun, Guoming, Ahn, Jeffrey M., Jiang, Nan, Ricupero, Christopher L., Wu, June, Rodhe, Christine Hsu, Ascherman, Jeffrey A., Chen, Lili, Mao, Jeremy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509822/
https://ncbi.nlm.nih.gov/pubmed/26010009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2052
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