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New classes of self-cleaving ribozymes revealed by comparative genomics analysis

Enzymes made of RNA catalyze reactions that are essential for protein synthesis and RNA processing. However, such natural ribozymes are exceedingly rare, as evident by the fact that the discovery rate for new classes has dropped to one per decade from about one per year during the 1980s. Indeed, onl...

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Vydáno v:Nat Chem Biol
Hlavní autoři: Weinberg, Zasha, Kim, Peter B., Chen, Tony H., Li, Sanshu, Harris, Kimberly A., Lünse, Christina E., Breaker, Ronald R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509812/
https://ncbi.nlm.nih.gov/pubmed/26167874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1846
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