The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors

BACKGROUND: While angiogenesis inhibitors represent a viable cancer therapy, there is preclinical and clinical data to suggest that many tumors develop resistance to such treatments. Moreover, previous studies have revealed a complex association between autophagy and angiogenesis, and their collecti...

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Veröffentlicht in:Mol Cancer
Hauptverfasser: Pathania, Anup S, Wani, Zahoor A, Guru, Santosh K, Kumar, Suresh, Bhushan, Shashi, Korkaya, Hasan, Seals, Darren F, Kumar, Ajay, Mondhe, Dilip M, Ahmed, Zabeer, Chandan, Bal K, Malik, Fayaz
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509694/
https://ncbi.nlm.nih.gov/pubmed/25608686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-14-6
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