Mapping nucleosome resolution chromosome folding in yeast by Micro-C

We describe a Hi-C based method, Micro-C, in which micrococcal nuclease is used instead of restriction enzymes to fragment chromatin, enabling nucleosome resolution chromosome folding maps. Analysis of Micro-C maps for budding yeast reveals abundant self-associating domains similar to those reported...

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Gepubliceerd in:Cell
Hoofdauteurs: Hsieh, Tsung-Han S., Weiner, Assaf, Lajoie, Bryan, Dekker, Job, Friedman, Nir, Rando, Oliver J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509605/
https://ncbi.nlm.nih.gov/pubmed/26119342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.048
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