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Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells
Transposable elements (TEs) comprise roughly forty per cent of mammalian genomes(1). TEs have played an active role in genetic variation, adaptation, and evolution through the duplication or deletion of genes or their regulatory elements(2-4) and TEs themselves can act as alternative promoters for n...
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| Опубликовано в: : | Nature |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4509593/ https://ncbi.nlm.nih.gov/pubmed/25938714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14345 |
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