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Saccharomyces cerevisiae Ski7 Is a GTP-Binding Protein Adopting the Characteristic Conformation of Active Translational GTPases

Ski7 is a cofactor of the cytoplasmic exosome in budding yeast, functioning in both mRNA turnover and non-stop decay (NSD), a surveillance pathway that degrades faulty mRNAs lacking a stop codon. The C-terminal region of Ski7 (Ski7(C)) shares overall sequence similarity with the translational GTPase...

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Publicat a:Structure
Autors principals: Kowalinski, Eva, Schuller, Anthony, Green, Rachel, Conti, Elena
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509514/
https://ncbi.nlm.nih.gov/pubmed/26051716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.018
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