Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia.

De novo methylation of CpG islands is a rare event in mammalian cells. It has been observed in the course of developmental processes, such as X chromosome inactivation and genomic imprinting. The methylation of DNA, an important factor in the epigenetic control of gene expression, may also be involv...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Zion, M, Ben-Yehuda, D, Avraham, A, Cohen, O, Wetzler, M, Melloul, D, Ben-Neriah, Y
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7938018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10722
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