Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia.
De novo methylation of CpG islands is a rare event in mammalian cells. It has been observed in the course of developmental processes, such as X chromosome inactivation and genomic imprinting. The methylation of DNA, an important factor in the epigenetic control of gene expression, may also be involv...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1994
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7938018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10722 |
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