The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells

Deubiquitinating enzymes (DUBs) negatively regulate protein ubiquitination and play an important role in diverse physiological processes, including mitotic division. The BRCC36 isopeptidase complex (BRISC) is a DUB that is specific for lysine 63–linked ubiquitin hydrolysis; however, its biological f...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Yan, Kaowen, Li, Li, Wang, Xiaojian, Hong, Ruisha, Zhang, Ying, Yang, Hua, Lin, Ming, Zhang, Sha, He, Qihua, Zheng, Duo, Tang, Jun, Yin, Yuxin, Shao, Genze
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508884/
https://ncbi.nlm.nih.gov/pubmed/26195665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503039
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