The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells

Deubiquitinating enzymes (DUBs) negatively regulate protein ubiquitination and play an important role in diverse physiological processes, including mitotic division. The BRCC36 isopeptidase complex (BRISC) is a DUB that is specific for lysine 63–linked ubiquitin hydrolysis; however, its biological f...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Yan, Kaowen, Li, Li, Wang, Xiaojian, Hong, Ruisha, Zhang, Ying, Yang, Hua, Lin, Ming, Zhang, Sha, He, Qihua, Zheng, Duo, Tang, Jun, Yin, Yuxin, Shao, Genze
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2015
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508884/
https://ncbi.nlm.nih.gov/pubmed/26195665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201503039
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