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Downregulating viral gene expression: codon usage bias manipulation for the generation of novel influenza A virus vaccines

Vaccination represents the best option to protect humans against influenza virus. However, improving the effectiveness of current vaccines could better stifle the health burden caused by viral infection. Protein synthesis from individual genes can be downregulated by synthetically deoptimizing a gen...

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Detalhes bibliográficos
Publicado no:Future Virol
Main Authors: Baker, Steven F, Nogales, Aitor, Martínez-Sobrido, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508661/
https://ncbi.nlm.nih.gov/pubmed/26213563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.15.31
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