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Novel Protein Kinase C-Mediated Control of Orai1 Function in Invasive Melanoma

The incidence of malignant melanoma, a cancer of the melanocyte cell lineage, has nearly doubled in the past 20 years. Wnt5A, a key driver of melanoma invasiveness, induces Ca(2+) signals. To understand how store-operated calcium entry (SOCE) contributes to Wnt5A-induced malignancy in melanoma model...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Hooper, Robert, Zhang, Xuexin, Webster, Marie, Go, Christina, Kedra, Joseph, Marchbank, Katie, Gill, Donald L., Weeraratna, Ashani T., Trebak, Mohamed, Soboloff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508319/
https://ncbi.nlm.nih.gov/pubmed/26055321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01500-14
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