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Smad7 Modulates Epidermal Growth Factor Receptor Turnover through Sequestration of c-Cbl

Epidermal growth factor (EGF) regulates various cellular events, including proliferation, differentiation, migration, and tumorigenesis. For the maintenance of homeostasis, EGF signaling should be tightly regulated to prevent the aberrant activation. Smad7 has been known as inhibitory Smad that bloc...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ha Thi, Huyen Trang, Kim, Hye-Youn, Choi, Seo-Won, Kang, Jin-Muk, Kim, Seong-Jin, Hong, Suntaek
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508311/
https://ncbi.nlm.nih.gov/pubmed/26055326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00274-15
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